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A team of researchers at Imperial College London UK led by Dr Andrew de Mello are working on a project developing a 'self diagnosis' chip.

It is envisaged that the chip's role would be to speed up the analysis of DNA. The chip has molecules traveling along its channels instead of electrons. Chemical reactions can be set off in the chip by coating the channels with catalysts.

The Imperial chip is the size of a postage stamp.  It may help patients analyse their own blood chemistry and make diagnoses.

The team at Imperial College believes that this chip could be an important diagnostic tool in the fight against disease.

The chip may have a significant potential in the genome project as it will have the technology to analyse mutations in DNA sequences.

A Centre for Integrated Genetic and Microchemical Analysis is to be set up at Imperial College to continue research and development of the chip.


Chemical Amplification: Continuous-Flow PCR on a Chip, Martin U. Kopp, Andrew J. de Mello, and Andreas Manz, Science 1998 May 15; 280: 1046-1048


Added  07 June 2004